Stuttgart, Germany - October 2008

Largest Update Since Launch of Pharmaceutical Substances

Stuttgart, Germany - Thieme Publishing Group has announced the largest update to Pharmaceutical Substances since its launch in 2003. Pharmaceutical Substances Version 3.1, available via Thieme-connect (www.thieme-connect.com), is a comprehensive reference guide to every significant pharmaceutical compound and includes all FDA approved active pharmaceutical ingredients (APIs).

Dr. Krimmer, Director Institutional Marketing, who manages the Pharmaceutical Substances project at Thieme states, "With 51 completely new and some 1,300 fully updated drug monographs, Pharmaceutical Substances Version 3.1 is the most up-to-date resource for researchers in industry and academic institutions involved in the synthesis of active pharmaceutical substances. We greatly appreciate the excellent work of our authors Professors Kleemann, Engel, Kutscher and Dr. Reichert as well as our cooperation partners FIZ Chemie and InfoChem who all worked on very tight deadlines to make this new release happen."

More than half of the entries have been revised in version 3.1. The substantial revisions include information regarding patents, literature, medical use, as well as trade and vendor names.

Compiled by leaders in the filed of pharmaceutical chemistry in association with InfoChem (www.infochem.de) and FIZ Chemie, the online version of the information resource is an easy-to-navigate, web-based portal that utilizes standard browser technology. The user-friendly interface lets you rapidly locate data and graphically search structures.

"As a process research and development chemist, I appreciate the detailed reaction schemes which inform me on how every drug on the market can be made and the detailed references to, not only the published literature, but to patents," states Dr. Trevor Laird, Scientific Update LLP and Editor of Organic Process Research and Development.

Pharmaceutical Substances provides a compendium of 2461 APIs of interest to the chemical and pharmaceutical industries. It is an invaluable resource for anyone and everyone involved in the design, synthesis, development, and evaluation of drugs.


About InfoChem
InfoChem GmbH (www.infochem.de), based in Munich, Germany, is a market leader in structure and reaction handling and retrieval. Founded in 1989, InfoChem focuses on the production and marketing of new chemical information products, including structural and reaction databases, and the development of software tools required for these applications. The main software tools provided are the InfoChem Fast Search Engine (ICFSE), the InfoChem Chemistry Cartridge for Oracle (ICCARTRIDGE), the reaction center identification (ICMAP) and the widely used InfoChem reaction classification algorithm CLASSIFY. In addition, InfoChem distributes one of the largest structural and reaction files worldwide, currently containing 6 million organic and organometallic compounds and facts and 4 million reactions covering the chemical literature published since 1974 (SPRESI). InfoChem's customers are large chemical and pharmaceutical companies as well as small high-potential start-ups worldwide. Springer-Verlag (Heidelberg) has held a majority interest in InfoChem since 1991.

About Thieme
Thieme Publishing Group is a privately held STM publishing house employing 900 people and maintaining offices in seven cities, including New York, Beijing, Delhi, Stuttgart and three other locations in Germany. Founded in 1886, the Thieme name has become synonymous with high quality and excellence in medical and scientific publishing. Today, Thieme is the market leading publisher of neurosurgical content and holds strong market positions in orthopedics, radiology, anatomy and chemistry, among other specialties. Thieme publishes 147 peer-reviewed journals and over 500 new books annually. The company also has a rapidly growing array of web-based products in medicine and science. Popular online products include Thieme eJournals and the Thieme Electronic Book Library, which are accessible via www.thieme-connect.com, Thieme's platform for electronic products. New anatomy resources include the www.thiemeteachingassistant.com for faculty, and www.winkingskull.com for students. Please visit www.thieme-connect.com for more information.


CONTACTS

Dr. Thomas Krimmer
Director Institutional Marketing
Thieme Publishing Group
Rüdigerstrasse 14
70469 Stuttgart
Germany
Tel. +49(0) 711 8931772
E-Mail: thomas.krimmer@thieme.de

Dr. Valentina Eigner Pitto
Director Marketing & Sales
InfoChem GmbH
Tel. +49(0) 89 583002
valentina.eigner-pitto@infochem.de