ICSYNTH

InfoChem's ICSYNTH is a powerful synthesis planning software tool developed to facilitate the work of bench chemists. This system is able to suggest synthesis strategies to a target molecule, based only on fully algorithmic chemical knowledge.
Multistep, interactive synthesis trees are generated automatically, based on different synthesis strategies, that users can select, depending on their needs.

ICSYNTH offers a new approach to synthesis planning with many advantages, such as the automatic generation of transform libraries, limited only by the access to validated reaction databases. In addition, the suggested reactions are always based, and have a link to, published reactions (or their analogous) and the precursor availability is automatically checked in catalogs.

Version 1.4 of ICSYNTH was launched in September 2011. Major improvements in the algorithm responsible of the precursor search and the possibility of grouping precursors according to the core structure or to the set of created bonds are the main enhancements of Version 1.4. In addition detail of the ratings for the different synthesis paths can now be exported.

How does it work?

ICSYNTH takes advantage of the automatic generation of chemically meaningfull precursors from accredited reaction databases (license required), such as:

• SPRESI
• Name Reactions
• Science of Synthesis (Thieme)
• ChemInform

The transform libraries produced during the automatic process are the basis for the chemical knowledge of the software.
Furthermore, a direct link from the suggested transformation to the original reaction described in the literature enables the user to decide if the proposed synthesis path is acceptable.

System Requirements

• Supported Browsers: Internet Explorer 5.5 or higher, Firefox (Windows, Mac OS X, Linux), Opera, Safari (Mac OS X)
• Software: Java 5 (JavaScript must be enabled)



• Applet Runtime Memory should be increased to 256 MB

Further Information

•   More information about ICSYNTH (pdf-file, 0,2 MB)
• Video Tutorial (swf-file, 13,3 MB)
• Request more information
• Quote request

Last modification: September 26, 2011.